Committed to quality and excellence in the development of affordable stem cell treatments for osteoarthritis in animals.
Key Features of Our Product, ADStem
A novel allogeneic stem cell therapy for the treatment of osteoarthritis in animals
Convenient and ready to use
Sterile, single dose packaging, long shelf life whilst deep frozen.
Efficient and safe
Our clinical trials to date show a long-lasting effect and little to no side effects.
One injection is sufficient to substantially reduce the symptoms of osteoarthritis and even promote healing.
We are developing mesenchymal stem cell-based products for the treatment of osteoarthritis in animals that are safe to use, readily available and provide long-term relief from pain and inflammation. Whilst our technology platform can be adapted to various species, our current focus is on developing a stem-cell product to treat osteoarthritis in dogs. We use allogeneic mesenchymal stem cells, obtained from healthy donors in a scalable and ethical production model.
Stem cells are unique in their ability to self-renew and differentiate into various cell types. Due to this stem cells can build new tissues in the body, that is why they have been of great interest to regenerative medicine and research.
ADStem – Stem cell therapy for dogs
- Novel treatment option including for non-specialist veterinary centres
- Stem cells from healthy donors with no history of osteoarthritis.
- Safe and ready to use; shelf life – 12 months+
- Single injection
- 150+ dogs treated in clinical research trials, up to 5 years follow-up
indicates long-term effectiveness
The Stem cellX team
Stem CellX comprises an international team of scientists in the fields of stem cells, regenerative medicine and genetics, working in collaboration with veterinarians to develop novel solutions to treat lameness in dogs and horses caused by mild osteoarthritis.
Founder & CEO of Stem CellX
Endre graduated as a Molecular Biologist in Hungary and obtained his PhD from the Hungarian Academy of Sciences. He then moved to Sheffield and established his own research group within the Medical School at the University of Sheffield and was Deputy Head of Department (2018-2021). He founded Stem CellX to develop novel, licensed regenerative therapies for Osteoarthritis.
Co-Founder & CSO of Stem CellX
Lajos is a Scientific Advisor at the Biological Research Centre of the Hungarian Academy of Sciences and alongside his research programme, he founded and leads Deltabio 2000 Limited, which developed the initial formulation of ADStem in collaboration with Endre Kiss-Toth, and led the early research trials. He co-founded Stem CellX to further develop ADStem into a fully licensed, commercial product.
Head of Regulatory Affairs
Paul has over 30 years of experience as a Veterinary Surgeon in varied technical roles in Corporate Animal Health, including >20 years in regulatory affairs at a senior level, followed by 10 years providing recognised RA consulting services through Assentra Ltd. Paul is a Past President of the Association of Veterinary Consultants.
Chief Financial Officer
Miklos is a Chartered Accountant and a former Corporate Finance Partner of PricewaterhouseCoopers and brings more than 29 years of business, financing and development experience to our team.
Head of Quality Control
Valeria has an MSc in molecular biology and is leading on the development of product quality control processes, including the GMP related aspects.
Head of Production
Eva has an MSc and a PhD degree in molecular biology. She has 10+ years experience in cell biology and is leading production developement strategies.
I could not let Bono live with perpetual pain, and removal of the detached cartilage chips would only have been a temporary solution. So I decided to try a stem-cell therapy. Stem cells cultured in the StemcellX laboratory were injected into the sick elbow joint by Bono’s veterinarian.
The result is rousing: since transplantation (2013) Bono has been living without pain, with no medication. It is true that he will never be a frisbee or agility champion, but he feels good and lives a nearly full life.